Pronounced: am’i-loy-dō’sisEn Español (Spanish Version)
Amyloidosis is a group of rare diseases. It involves deposits of a protein called amyloid. These proteins build up in body tissues and organs. There are three major forms:
- Primary amyloidosis—found in the heart, lungs, skin, tongue, thyroid gland, intestines, liver, kidneys, and blood vessels
- Secondary amyloidosis—found in the spleen, liver, kidneys, adrenal glands, and lymph nodes
- Hereditary amyloidosis—found in the nerves, heart, blood vessels, and kidneys
The build up of amyloid can make it difficult for the organ or tissue to function. These conditions are serious. They require care from your doctor.
The causes of amyloidosis vary in its different forms.
- Primary amyloidosis—caused by the deposit of antibody fragments; associated with bone marrow disorders (eg, multiple myeloma)
- Secondary amyloidosis—develops in response to chronic infection or inflammatory disease
- Hereditary amyloidosis—caused by mutations of amyloid in the blood
Last reviewedMarch 2013by Igor Puzanov, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.